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China began to open to the outside world in the late 1970s. _________, there have been great changes in the country.                  
A.By thenB.As a resultC. At last D.In all
B

试题分析:句意:在20世纪70年代后期,中国开始对外开放。结果中国发生了很大的变化。by then 到那时为止;as a result 结果是……; at last 最后;in all 总而言之。根据句意可知,对外开放的结果是让中国发生了巨大的变化。故选B。
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