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--- Doctor, ________ should I take this medicine?    --- Twice a day.
A.how oftenB.how muchC.how soonD.what time
A

试题分析:句意:——医生,我应该多久吃一次药?—— 一天两次。A. how often 多久一次(就频率来提问);B. how much 多少(就价钱来提问或者修饰不可数名词);C. how soon 还要多久(常用在一般将来时态的句子中,其答语通常是“in + 一段时间”);D. what time几点,根据一天两次,可知就频率来提问,故选择A。
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