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---What’s wrong ______ Maria?  ---She has a cold.
A. with      B. of     C. about
A

试题分析:What's wrong with sb.?是问某人怎么了。本句型是固定用法。所以本题选A。
点评:应该熟练掌握常用句型的用法,注意词语的固定搭配。
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