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One of the most important problems they had to consider was________of public health.
A.whatB.thisC.thatD.which
C
C [句意:他们必须考虑的最重要的问题之一是大众健康。句中缺少表语,且指代上文one of the most important problems,所以应用that。what和which不能用作替代词,而this作代词时指代下文。]
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