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    It is uncertain side effect the medicine will bring about , though about one thousand patients have taken it.

    A. that B. whether C. what D. how

     

    C

    【解析】

    试题分析:句意：尽管大约一千名病人已经服用了这种药物，但是还不能确定这种药会产生什么副作用。根据结构可知it是形式主语，真正的主语是___side effect the medicine will bring about ,主语从句中缺少bring about 的宾语，应该用连接代词，故答案选C。

    考点：考查名词性从句。

     

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