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It is uncertain           side effect the medicine will bring about, although about two thousand patients have taken it.


  1. A.
    that
  2. B.
    what
  3. C.
    how
  4. D.
    whether
B
考查宾语从句。宾语从句中 bring about后缺少宾语,故用what 作定语修饰side effect,句意:还不清楚这种药会带来什么样的副作用,虽然大约两千名病人已经服用过。故选B。
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