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his knowledge of the mountainous village, John was appointed as our guide.

A. In spite of B. On account of

C. Regardless of D. Instead of

B

【解析】

试题分析:考查介词短语的辨析。In spite of虽然,尽管…;On account of考虑到,基于,由于;Regardless of不管,不顾;Instead of代替,而不是。句意:考虑到他对乡村知识的了解,John被任命为我们的向导。故选B。

考点:考查介词短语的辨析

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