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    It is uncertain      side effect the medicine will bring about , though about one thousand patients have taken it.
    A．thatB．whetherC．whatD．how
    C

    试题分析：句意：尽管大约1000名病人使用了这种药，但它会带来什么样的副作用还不清楚。此处what修饰名词side effect。故选C。
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