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My sister has some trouble ______spelling some of the words in American English, while I have some difficulty ________ my pronunciation.

A.with; with B.in; with C.with; in D.in; in 

B

解析试题分析:考查短语中介词搭配的区别。have trouble/difficulty with sth./(in)doing sth.做某事有困难,特别注意in后面接Ving;with后面接名词,从题干来看,第一空后是spelling,要选in;第二空后是my pronunciation为名词,选with;故B正确。
考点:考查短语中介词搭配的区别。

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