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______ piano is her main focus, she's also great at guitar.

A.Since B.Once C.Unless D.While 

D

解析试题分析:考查让步状语从句。句意:尽管钢琴是她的主修,但是她也擅长弹吉他。A既然,自从;B一旦;C除非;D尽管。since引导原因状语从句或时间状语从句;once和unless表示条件;while在此表示让步。故选D。
考点:考查让步状语从句

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