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--- Did Tony win the game?
--- No. Staying up late made him at his worst _____ physical situation.

A.in case of B.in terms of C.in favor of D.in spite of

B

解析试题分析:A. in case of如果,万一,B. in terms of 就…而言,C. in favor of支持,赞同,D. in spite of虽然,句意:—Tony赢得了比赛吗?--没有熬夜使他就身体状况而言是最糟糕的。所以选B。
考点:考查介词短语

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