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—What has  made him look like lacking sleep?
—_______ his wife is ill and he has to get up several times a night to attend to her.
A.ForB.BecauseC.ThatD.What
C

试题分析:考察名词性从句关系词 句意为:---是什么导致他看上去缺乏睡眠呢 
----他的妻子病了,他得每天起夜几次去照顾他生病的妻子
That做为名词性从句的引导词,起连接作用,本身无实际意义。从语法关系上看,that从句相当于名词的功能。根据上句what可判断,下句应是一个在语法上充当主语的句子成分。故C选项符合题意
考点:考察名词性从句关系词    
点评:考生在解答此类型题目,应从上下句的句法关系着手分析,切不可‘望句形生答案’总的来说,考生在解答此类型时,可用排除法或造句法,造句法就是仿造原句的语法功能仿造出一个易懂易理解的句子,帮助判断。
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